Bonding Bases

 

6. X-ray photographs

Maurice Wilkins had already succeeded in taking X-ray photographs of DNA crystals. He was now working with a trained crystallographer, Rosalind Franklin, trying to obtain better pictures which might give more clues to the structure.

Crick and Watson were not the only researchers interested in the photographs from King's College. Linus Pauling had asked if Wilkins would send him copies in California. Wilkins was hoping to find the structure himself, so told Pauling that the photographs weren't ready to be made public.

In November 1951 Watson went down to London to hear Franklin's preliminary report on her DNA photographs. It was clear that the researchers in London were still collecting X-ray crystallography data, and not yet suggesting possible structures for the molecule.

When Watson returned to Cambridge he told Crick about Franklin's photographs, but couldn't remember all the details. Crick felt that the photographs suggested DNA should be a helix, but could have two, three or four strands. They decided to start building models to see if they could find the structure.

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