Bonding Bases

Francis Crick & James Watson
having coffee in the Cavendish after publication of their discovery

15. Living with a Double Helix

Over the next few days Watson and Crick assembled a large model of the DNA structure, and were ready to announce their discovery. Wilkins visited from London and offered to compare the X-ray data with this new structure. A few days later he 'phoned back to announce that both he and Franklin agreed that their data was in strong support of the double helix.

Both laboratories agreed to publish their results simultaneously. Watson and Crick wrote a paper on the structure of DNA, while Wilkins and Franklin prepared two papers about their X-ray photographs. All three articles were published together in the journal Nature on 25th April, 1953.

In 1962 Watson, Crick and Wilkins received the Nobel Prize for Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material". Sadly Rosalind Franklin could not share in the prize. She had become ill with cancer in 1956, and died two years later, before the prize was awarded. Her essential role in the discovery of DNA's molecular structure was never disputed.

Max Perutz's team in the Cavendish grew rapidly after the discovery. The year before Watson's arrival only four molecular biologists were working in the Cavendish, but only ten years later this number had grown to forty! In 1962 the molecular biologists moved out of the Cavendish to form the Medical Research Council Laboratory of Molecular Biology, chaired by Perutz until his retirement in 1979. At the start of 2001 there were over four hundred molecular biologists in the MRC Laboratory.

Next Page